Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats

Irritable bowel syndrome (IBS) is a common and debilitating gastrointestinal disorder that is exacerbated by stress and characterized by abdominal pain. Although microglia in the CNS have been implicated as an important mediator of the stress response, the role of microglia and microglia-GABAergic n...

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Bibliographic Details
Main Authors: Ning-Ning Ji, Qing-Xiang Meng, Ying Wang, Zi-Ming Zhou, Yu Song, Rong Hua, Yong-Mei Zhang
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Neurobiology of Stress
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289522000248