Structure of the RNA-dependent RNA polymerase P2 from the cystovirus φ8

Abstract The replication of RNA viruses relies on the activity of RNA-dependent RNA polymerases (RdRps). Despite large variations in their genomic sequences, viral RdRps share a common architecture generally known as a closed right hand. The P2 polymerase of cystovirus φ6 is currently among the best...

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Bibliographic Details
Main Authors: Merlyn Latimer-Smith, Paula S. Salgado, Ismay Forsyth, Eugene Makeyev, Minna M. Poranen, Dave I. Stuart, Jonathan M. Grimes, Kamel El Omari
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-75213-7