Development of immunotherapy for high-grade gliomas: Overcoming the immunosuppressive tumor microenvironment

Development of immunotherapy for high-grade gliomas: Overcoming the immunosuppressive tumor microenvironment

The preclinical and clinical development of novel immunotherapies for the treatment of central nervous system (CNS) tumors is advancing at a rapid pace. High-grade gliomas (HGG) are aggressive tumors with poor prognoses in both adult and pediatric patients, and innovative and effective therapies are...

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Bibliographic Details
Main Authors: Andrea Franson, Brandon L. McClellan, Maria Luisa Varela, Andrea Comba, Mohammad Faisal Syed, Kaushik Banerjee, Ziwen Zhu, Nazareno Gonzalez, Marianela Candolfi, Pedro Lowenstein, Maria Graciela Castro
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Medicine
Subjects:
gliomas
immunotherapy
tumor microenvironment
gene therapy
immune suppression
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.966458/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.966458/full

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