Effects of Leptin and Body Weight on Inflammation and Knee Osteoarthritis Phenotypes in Female Rats

ABSTRACT Leptin is a proinflammatory adipokine that contributes to obesity‐associated osteoarthritis (OA), especially in women. However, the extent to which leptin causes knee OA separate from the effect of increased body weight is not clear. We hypothesized that leptin is necessary to induce knee O...

Full description

Bibliographic Details
Main Authors: Yao Fu, Albert Batushansky, Michael Kinter, Janet L. Huebner, Virginia B. Kraus, Timothy M. Griffin
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:JBMR Plus
Subjects:
Online Access:https://doi.org/10.1002/jbm4.10754