Effects of Leptin and Body Weight on Inflammation and Knee Osteoarthritis Phenotypes in Female Rats
ABSTRACT Leptin is a proinflammatory adipokine that contributes to obesity‐associated osteoarthritis (OA), especially in women. However, the extent to which leptin causes knee OA separate from the effect of increased body weight is not clear. We hypothesized that leptin is necessary to induce knee O...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-07-01
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Series: | JBMR Plus |
Subjects: | |
Online Access: | https://doi.org/10.1002/jbm4.10754 |