Insights from the protein interaction Universe of the multifunctional “Goldilocks” kinase DYRK1A

Human Dual specificity tyrosine (Y)-Regulated Kinase 1A (DYRK1A) is encoded by a dosage-dependent gene located in the Down syndrome critical region of human chromosome 21. The known substrates of DYRK1A include proteins involved in transcription, cell cycle control, DNA repair and other processes. H...

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Bibliographic Details
Main Authors: Varsha Ananthapadmanabhan, Kathryn H. Shows, Amanda J. Dickinson, Larisa Litovchick
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1277537/full