The Effects of the Combination of Mesenchymal Stromal Cells and Nanofiber-Hydrogel Composite on Repair of the Contused Spinal Cord

The Effects of the Combination of Mesenchymal Stromal Cells and Nanofiber-Hydrogel Composite on Repair of the Contused Spinal Cord

A bone marrow-derived mesenchymal stromal cell (MSC) transplant and a bioengineered nanofiber-hydrogel composite (NHC) have been shown to stimulate nervous tissue repair in the contused spinal cord in rodent models. Here, these two modalities were combined to assess their repair effects in the contu...

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Bibliographic Details
Main Authors: Agnes E. Haggerty, Ines Maldonado-Lasunción, Yohshiro Nitobe, Kentaro Yamane, Megan M. Marlow, Hua You, Chi Zhang, Brian Cho, Xiaowei Li, Sashank Reddy, Hai-Quan Mao, Martin Oudega
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
nanofiber-hydrogel composite
spinal cord injury
inflammation
macrophages
secondary injury
astrocytes
Online Access:https://www.mdpi.com/2073-4409/11/7/1137

Internet

https://www.mdpi.com/2073-4409/11/7/1137

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