Mode of Action Assignment of Chemicals Using Toxicogenomics: A Case Study with Oxidative Uncouplers
A criterion frequently used to group chemicals in risk assessment is “mode of toxic action” (MoA). Routinely, structure-based approaches are used for the MoA categorization of chemicals, but they can produce conflicting results or fail to classify compounds. Biological activity-based approaches such...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2017-11-01
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| Series: | Frontiers in Environmental Science |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fenvs.2017.00080/full |