ERK3/MAPK6 controls IL-8 production and chemotaxis

ERK3/MAPK6 controls IL-8 production and chemotaxis

ERK3 is a ubiquitously expressed member of the atypical mitogen activated protein kinases (MAPKs) and the physiological significance of its short half-life remains unclear. By employing gastrointestinal 3D organoids, we detect that ERK3 protein levels steadily decrease during epithelial differentiat...

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Bibliographic Details
Main Authors: Katarzyna Bogucka, Malvika Pompaiah, Federico Marini, Harald Binder, Gregory Harms, Manuel Kaulich, Matthias Klein, Christian Michel, Markus P Radsak, Sebastian Rosigkeit, Peter Grimminger, Hansjörg Schild, Krishnaraj Rajalingam
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
MAPK
ERK3
secretome
metastasis
signal transduction
chemotaxis
Online Access:https://elifesciences.org/articles/52511

Internet

https://elifesciences.org/articles/52511

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