Mitofusin 2-deficiency suppresses cell proliferation through disturbance of autophagy.

Mitofusin2 (Mfn2), a mitochondrial outer membrane protein serving primarily as a mitochondrial fusion protein, has multiple functions in regulating cell biological processes. Defects of Mfn2 were found in diabetes, obesity, and neurodegenerative diseases. In the present study, we found that knockdow...

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Bibliographic Details
Main Authors: Yanhong Ding, Han Gao, Lifang Zhao, Xian Wang, Ming Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4363693?pdf=render