Anti-CCL2 therapy reduces oxygen toxicity to the immature lung

Abstract Oxygen toxicity constitutes a key contributor to bronchopulmonary dysplasia (BPD). Critical step in the pathogenesis of BPD is the inflammatory response in the immature lung with the release of pro-inflammatory cytokines and the influx of innate immune cells. Identification of efficient the...

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Bibliographic Details
Main Authors: Tayyab Shahzad, Ying Dong, Nina K. Behnke, Julia Brandner, Anne Hilgendorff, Cho-Ming Chao, Judith Behnke, Saverio Bellusci, Harald Ehrhardt
Format: Article
Language:English
Published: Nature Publishing Group 2024-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02073-5