Optimization of a novel expression system for recombinant protein production in CHO cells

Optimization of a novel expression system for recombinant protein production in CHO cells

Abstract Chinese hamster ovary (CHO) cells are common mammalian cell lines for expressing recombinant proteins, yet the expression level of recombinant proteins is still hindered. Vector optimization and cell line modification are the key factors to improve the expression of recombinant proteins. In...

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Bibliográfalaš dieđut
Váldodahkkit: Junhe Zhang, Chenyang Du, Yue Pan, Zhan Zhang, Ruoyuan Feng, Mengyao Ma, Tianyun Wang
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Nature Portfolio 2024-10-01
Ráidu:Scientific Reports
Fáttát:
CHO cells
Vector optimization
CRISPR/Cas9
Recombinant protein
Liŋkkat:https://doi.org/10.1038/s41598-024-76995-6

Interneahtta

https://doi.org/10.1038/s41598-024-76995-6

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