Metabolic reprogramming, autophagy, and ferroptosis: Novel arsenals to overcome immunotherapy resistance in gastrointestinal cancer

Abstract Background Gastrointestinal cancer poses a serious health threat owing to its high morbidity and mortality. Although immune checkpoint blockade (ICB) therapies have achieved meaningful success in most solid tumors, the improvement in survival in gastrointestinal cancers is modest, owing to...

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Bibliographic Details
Main Authors: Xiangwen Wang, Liwen Zhou, Hongpeng Wang, Wei Chen, Lei Jiang, Guangtao Ming, Jun Wang
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.6623