Transcriptomics-based analysis of sex-differentiated mechanisms of hepatotoxicity in zebrafish after long-term exposure to bisphenol AF

Transcriptomics-based analysis of sex-differentiated mechanisms of hepatotoxicity in zebrafish after long-term exposure to bisphenol AF

Bisphenol AF (BPAF) is an emerging endocrine-disrupting chemical (EDC) prevalent in the environment as one of the main substitutes for bisphenol A. Sex-specific effects of EDCs have been commonly reported and closely linked to sexually dimorphic patterns of hormone metabolism and related gene expres...

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Bibliographic Details
Main Authors: Xiaoyu Zhao, Yuanyuan Zhang, Ting Yu, Ling Cai, Junlang Liang, Zhong Chen, Chenyuan Pan, Ming Yang
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Environmental estrogens
Adverse outcome pathway (AOP) analysis
Liver toxicity
Sexual dimorphism
RNA sequencing
Teleosts
Online Access:http://www.sciencedirect.com/science/article/pii/S014765132300828X

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http://www.sciencedirect.com/science/article/pii/S014765132300828X

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