Excessive linoleic acid induces muscle oxidative stress through 5-lipoxygenase-dependent peroxidation

Excessive linoleic acid induces muscle oxidative stress through 5-lipoxygenase-dependent peroxidation

Oxidative stress in muscles is closely related to the occurrence of insulin resistance, muscle weakness and atrophy, age-related sarcopenia, and cancer. Aldehydes, a primary oxidation intermediate of polyunsaturated fatty acids, have been proven to be an important trigger for oxidative stress. Howev...

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Bibliographic Details
Main Authors: Xiufei Cao, Huixing Guo, Yongjun Dai, Guangzhen Jiang, Wenbin Liu, Xiangfei Li, Dingdong Zhang, Yangyang Huang, Xi Wang, Haokun Hua, Jianfeng Wang, Keke Chen, Cheng Chi, Hengtong Liu
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Redox Biology
Subjects:
Crab muscle
Linoleic acid
Oxidative stress
Volatile aldehydes
5-Lipoxygenase
cAMP/PKA signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724000727

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http://www.sciencedirect.com/science/article/pii/S2213231724000727

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