Cryo-Electron Tomography of the Herpesvirus Procapsid Reveals Interactions of the Portal with the Scaffold and a Shift on Maturation

Herpes simplex virus 1 (HSV-1) infects a majority of humans, causing mostly mild disease but in some cases progressing toward life-threatening encephalitis. Understanding the life cycle of the virus is important to devise countermeasures.

Bibliographic Details
Main Authors: Michael H. C. Buch, William W. Newcomb, Dennis C. Winkler, Alasdair C. Steven, J. Bernard Heymann
Format: Article
Language:English
Published: American Society for Microbiology 2021-04-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.03575-20