Increased expression of AQP 1 and AQP 5 in rat lungs ventilated with low tidal volume is time dependent.

BACKGROUND AND GOALS: Mechanical ventilation (MV) can induce or worsen pulmonary oedema. Aquaporins (AQPs) facilitate the selective and rapid bi-directional movement of water. Their role in the development and resolution of pulmonary oedema is controversial. Our objectives are to determine if prolon...

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Bibliographic Details
Main Authors: Gustavo Fabregat, José García-de-la-Asunción, Benjamín Sarriá, Julio Cortijo, José De Andrés, Manuel Mata, Ernesto Pastor, Francisco Javier Belda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4260863?pdf=render