PACAP-deficient mice exhibit light parameter-dependent abnormalities on nonvisual photoreception and early activity onset.

BACKGROUND: The photopigment melanopsin has been suggested to act as a dominant photoreceptor in nonvisual photoreception including resetting of the circadian clock (entrainment), direct tuning or masking of vital status (activity, sleep/wake cycles, etc.), and the pupillary light reflex (PLR). Pitu...

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Bibliographic Details
Main Authors: Chihiro Kawaguchi, Yasushi Isojima, Norihito Shintani, Michiyoshi Hatanaka, Xiaohong Guo, Nobuaki Okumura, Katsuya Nagai, Hitoshi Hashimoto, Akemichi Baba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2823792?pdf=render