CC chemokine receptor 7 promotes macrophage recruitment and induces M2-polarization through CC chemokine ligand 19&21 in oral squamous cell carcinoma

CC chemokine receptor 7 promotes macrophage recruitment and induces M2-polarization through CC chemokine ligand 19&21 in oral squamous cell carcinoma

Abstract Purpose This study aimed to investigate the impact of CC chemokine receptor 7 (CCR7) on the recruitment and polarization of tumor-associated macrophages (TAMs) in oral squamous cell carcinoma (OSCC). Methods We analyzed CCR7 expression pattern, clinicopathological significance, and its asso...

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Bibliographic Details
Main Authors: Wan-Hang Zhou, Yao Wang, Cong Yan, Wei-Dong Du, Maged Ali Al-Aroomi, Li Zheng, Shan-Feng Lin, Jia-Xing Gao, Sheng Jiang, Zeng-Xu Wang, Chang-Fu Sun, Fa-Yu Liu
Format: Article
Language:English
Published: Springer 2022-07-01
Series:Discover Oncology
Subjects:
CCR7
Macrophage
Recruitment
Polarization
Oral squamous cell carcinoma
Online Access:https://doi.org/10.1007/s12672-022-00533-x

Internet

https://doi.org/10.1007/s12672-022-00533-x

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