Histone Deacetylase Inhibitors Sensitize TRAIL-Induced Apoptosis in Colon Cancer Cells

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered as a promising anti-cancer therapeutic. However, many cancers have been found to be or to become inherently resistant to TRAIL. A combination of epigenetic modifiers, such as histone deacetylase inhibitors (HDACi&#8217...

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Bibliographic Details
Main Authors: Baojie Zhang, Bin Liu, Deng Chen, Rita Setroikromo, Hidde J. Haisma, Wim J. Quax
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/5/645