Efficacy of Phase I and Phase II <i>Coxiella burnetii</i> Bacterin Vaccines in a Pregnant Ewe Challenge Model

Efficacy of Phase I and Phase II <i>Coxiella burnetii</i> Bacterin Vaccines in a Pregnant Ewe Challenge Model

The bacterium <i>Coxiella burnetii</i> can cause the disease Q-fever in a wide range of animal hosts. Ruminants, including sheep, are thought to play a pivotal role in the transmission of <i>C. burnetii</i> to humans; however, the only existing livestock vaccine, namely, Coxe...

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Bibliographic Details
Main Authors: Sarah E. Williams-Macdonald, Mairi Mitchell, David Frew, Javier Palarea-Albaladejo, David Ewing, William T. Golde, David Longbottom, Alasdair J. Nisbet, Morag Livingstone, Clare M. Hamilton, Stephen F. Fitzgerald, Søren Buus, Emil Bach, Annemieke Dinkla, Hendrik-Jan Roest, Ad P. Koets, Tom N. McNeilly
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Vaccines
Subjects:
Q-fever
<i>Coxiella burnetii</i>
vaccine
sheep
phase I
phase II
Online Access:https://www.mdpi.com/2076-393X/11/3/511

Internet

https://www.mdpi.com/2076-393X/11/3/511

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