Cellular senescence and SASP in tumor progression and therapeutic opportunities
Abstract Cellular senescence (CS), a permanent and irreversible arrest of the cell cycle and proliferation leading to the degeneration of cellular structure and function, has been implicated in various key physiological and pathological processes, particularly in cancer. Initially, CS was recognized...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-08-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12943-024-02096-7 |