Catalpol relieved angiotensin II-induced blood–brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells

Catalpol relieved angiotensin II-induced blood–brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells

Context Catalpol is a major bioactive constituent of Rehmannia glutinosa Libosch (Scrophulariaceae), a traditional Chinese medicine, which is widely used in multiple diseases, including hypertension.Objectives To explore whether catalpol protects against angiotensin II (Ang II)-triggered blood–brain...

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Bibliographic Details
Main Authors: Yu Xia, Yun Wei Lu, Ren Juan Hao, Gu Ran Yu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Pharmaceutical Biology
Subjects:
Hypertension
cerebral small vessel disease
inflammation
transcytosis
bEnd.3
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2022.2142801

Internet

https://www.tandfonline.com/doi/10.1080/13880209.2022.2142801

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