Specificity and functional interplay between influenza virus PA-X and NS1 shutoff activity.

Influenza A viruses modulate host antiviral responses to promote viral growth and pathogenicity. Through viral PA-X and NS1 proteins, the virus is capable of suppressing host protein synthesis, termed "host shutoff." Although both proteins are known to induce general shutoff, specificity o...

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Bibliografische gegevens
Hoofdauteurs: Chutikarn Chaimayo, Megan Dunagan, Tsuyoshi Hayashi, Netty Santoso, Toru Takimoto
Formaat: Artikel
Taal:English
Gepubliceerd in: Public Library of Science (PLoS) 2018-11-01
Reeks:PLoS Pathogens
Online toegang:https://doi.org/10.1371/journal.ppat.1007465