Mapping out the gut microbiota-dependent trimethylamine N-oxide super pathway for systems biology applications

Mapping out the gut microbiota-dependent trimethylamine N-oxide super pathway for systems biology applications

The metabolic axis linking the gut microbiome and heart is increasingly being researched in the context of cardiovascular health. The gut microbiota-derived trimethylamine/trimethylamine N-oxide (TMA/TMAO) pathway is responsible along this axis for the bioconversion of dietary precursors into TMA/TM...

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Bibliographic Details
Main Authors: Isabel M. E. Valenbreder, Sonia Balăn, Marian Breuer, Michiel E. Adriaens
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Systems Biology
Subjects:
gut microbiome
TMA/TMAO pathway
constraint-based modeling
gut-heart axis
pathway
whole-body metabolic model
Online Access:https://www.frontiersin.org/articles/10.3389/fsysb.2023.1074749/full

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https://www.frontiersin.org/articles/10.3389/fsysb.2023.1074749/full

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