A Case of mistaken identity: Rhabdomyosarcoma development from endothelial progenitor cells

A Case of mistaken identity: Rhabdomyosarcoma development from endothelial progenitor cells

Rhabdomyosarcoma (RMS) histologically resembles developing skeletal muscle and is thought to solely originate from a differentiation block in muscle progenitors. We demonstrate that RMS can arise from endothelial progenitor cells following reprogramming and myogenic transdifferentiation. These resul...

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Bibliographic Details
Main Authors: Catherine J. Drummond, Mark E. Hatley
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Molecular & Cellular Oncology
Subjects:
cell of origin
endothelial
hedgehog
muscle
pediatric cancer
reprogramming
rhabdomyosarcoma
skeletal muscle
sarcoma
transdifferentiation
Online Access:http://dx.doi.org/10.1080/23723556.2018.1448246

Internet

http://dx.doi.org/10.1080/23723556.2018.1448246

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