Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca<sup>2+</sup> Influx

Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca<sup>2+</sup> Influx

Presynaptic Ca<sup>2+</sup> influx through voltage-gated Ca<sup>2+</sup> channels (VGCCs) is a key signal for synaptic vesicle release. Synaptic neurexins can partially determine the strength of transmission by regulating VGCCs. However, it is unknown whether neurexins modula...

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Bibliographic Details
Main Authors: Johannes Brockhaus, Iris Kahl, Mohiuddin Ahmad, Daniele Repetto, Carsten Reissner, Markus Missler
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Cells
Subjects:
neurexin
calcium channel subtypes
presynapse
endocannabinoid system
genetically encoded calcium indicator
Online Access:https://www.mdpi.com/2073-4409/13/11/981

Internet

https://www.mdpi.com/2073-4409/13/11/981

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