DFMG decreases angiogenesis to uphold plaque stability by inhibiting the TLR4/VEGF pathway in mice.

DFMG decreases angiogenesis to uphold plaque stability by inhibiting the TLR4/VEGF pathway in mice.

The aim of this study was to elucidate the specific mechanism through which 7-difluoromethoxy-5,4'-dimethoxygenistein (DFMG) inhibits angiogenesis in atherosclerosis (AS) plaques, given its previously observed but poorly understood inhibitory effects. In vitro, a model using Human Umbilical Vei...

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Bibliographic Details
Main Authors: Pingjuan Bai, Xueping Xiang, Jiawen Kang, Xiaoqing Xiang, Jingwen Jiang, Xiaohua Fu, Yong Zhang, Lesai Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0302387&type=printable

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0302387&type=printable

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