Differential Virulence of Aggregatibacter actinomycetemcomitans Serotypes Explained by Exoproteome Heterogeneity

ABSTRACT Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative bacterial pathogen associated with periodontitis and nonoral diseases like rheumatoid arthritis and Alzheimer´s disease. Aa isolates with the serotypes a, b, and c are globally most prevalent. Importantly, isolates displaying the...

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Bibliographic Details
Main Authors: Yanyan Fu, Sandra Maaβ, Francis M. Cavallo, Anne de Jong, Erwin Raangs, Johanna Westra, Girbe Buist, Dörte Becher, Jan Maarten van Dijl
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03298-22