Proteomic characterization of esophageal squamous cell carcinoma response to immunotherapy reveals potential therapeutic strategy and predictive biomarkers

Proteomic characterization of esophageal squamous cell carcinoma response to immunotherapy reveals potential therapeutic strategy and predictive biomarkers

Abstract Immunotherapy is the first-line therapy for esophageal squamous cell carcinoma (ESCC), yet many patients do not respond due to drug resistance and the lack of reliable predictive markers. We collected 73 ESCC patients (including discovery cohort and validation cohort) without immune thrombo...

Celý popis

Podrobná bibliografie
Hlavní autoři: Fahan Ma, Yan Li, Chan Xiang, Bing Wang, Jie Lv, Jinzhi Wei, Zhaoyu Qin, Yan Pu, Kai Li, Haohua Teng, Subei Tan, Jinwen Feng, Zhanxian Shang, Yunzhi Wang, Sha Tian, Changsheng Du, Yuchen Han, Chen Ding
Médium: Článek
Jazyk:English
Vydáno: BMC 2024-03-01
Edice:Journal of Hematology & Oncology
Témata:
Esophageal squamous cell carcinoma
Proteomics
Anti-PD1 immunotherapy
Platelets activation
Predictive markers
Immunotherapy response prediction
On-line přístup:https://doi.org/10.1186/s13045-024-01534-9

Internet

https://doi.org/10.1186/s13045-024-01534-9

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