Quantitative systems pharmacology modeling sheds light into the dose response relationship of a trispecific T cell engager in multiple myeloma

Quantitative systems pharmacology modeling sheds light into the dose response relationship of a trispecific T cell engager in multiple myeloma

Abstract In relapsed and refractory multiple myeloma (RRMM), there are few treatment options once patients progress from the established standard of care. Several bispecific T-cell engagers (TCE) are in clinical development for multiple myeloma (MM), designed to promote T-cell activation and tumor k...

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Bibliographic Details
Main Authors: R. E. Abrams, K. Pierre, N. El-Murr, E. Seung, L. Wu, E. Luna, R. Mehta, J. Li, K. Larabi, M. Ahmed, V. Pelekanou, Z.-Y. Yang, H. van de Velde, S. K. Stamatelos
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-14726-5

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https://doi.org/10.1038/s41598-022-14726-5

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