Distinct Roles for COMPASS Core Subunits Set1, Trx, and Trr in the Epigenetic Regulation of <i>Drosophila</i> Heart Development

Distinct Roles for COMPASS Core Subunits Set1, Trx, and Trr in the Epigenetic Regulation of <i>Drosophila</i> Heart Development

Highly evolutionarily conserved multiprotein complexes termed Complex of Proteins Associated with Set1 (COMPASS) are required for histone 3 lysine 4 (H3K4) methylation. <i>Drosophila</i> Set1, Trx, and Trr form the core subunits of these complexes. We show that flies deficient in any of...

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Bibliographic Details
Main Authors: Jun-yi Zhu, Hangnoh Lee, Xiaohu Huang, Joyce van de Leemput, Zhe Han
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
heart development
histone modification
<i>Drosophila</i>
<i>Set1</i>
<i>trx</i>
<i>trr</i>
Online Access:https://www.mdpi.com/1422-0067/24/24/17314

Internet

https://www.mdpi.com/1422-0067/24/24/17314

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