Substrate Stiffness Drives Epithelial to Mesenchymal Transition and Proliferation through the <i>NEAT1</i>-Wnt/β-Catenin Pathway in Liver Cancer

Background: Extracellular matrix (ECM)-derived mechanical stimuli regulate many cellular processes and phenotypes through mechanotransduction signaling pathways. Substrate stiffness changes cell phenotypes and promotes angiogenesis, epithelial to mesenchymal transition (EMT), and metastasis in tumor...

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Bibliographic Details
Main Authors: Xichao Xu, Yi Zhang, Xing Wang, Shun Li, Liling Tang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/21/12066