External Evaluation of Vancomycin Population Pharmacokinetic Models at Two Clinical Centers

Background: Numerous vancomycin population pharmacokinetic models in neonates have been published; however, their predictive performances remain unknown. This study aims to evaluate their external predictability and explore the factors that might affect model performance.Methods: Published populatio...

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Bibliographic Details
Main Authors: Yi-Xi Liu, Haini Wen, Wan-Jie Niu, Jing-Jing Li, Zhi-Ling Li, Zheng Jiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.623907/full