Effect of therapeutic plasma exchange on endothelial activation and coagulation-related parameters in septic shock

Abstract Background A dysbalanced coagulation system is part of the pathological host response to infection in sepsis. Activation of pro-coagulant pathways and attenuation of anti-coagulant activity ultimately lead to microvascular stasis and consequent organ failure. No treatment approaches specifi...

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Bibliographic Details
Main Authors: Klaus Stahl, Julius J. Schmidt, Benjamin Seeliger, Bernhard M. W. Schmidt, Tobias Welte, Hermann Haller, Marius M. Hoeper, Ulrich Budde, Christian Bode, Sascha David
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-020-2799-5