The GABAA Receptor Influences Pressure Overload-Induced Heart Failure by Modulating Macrophages in Mice

The GABAA Receptor Influences Pressure Overload-Induced Heart Failure by Modulating Macrophages in Mice

BackgroundMyocardial macrophages have key roles in cardiac remodeling and dysfunction. The gamma-aminobutyric acid subtype A (GABAA) receptor was recently found to be distributed in macrophages, allowing regulation of inflammatory responses to various diseases. This study aimed to clarify the role o...

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Bibliographic Details
Main Authors: Jin Bu, Shiyuan Huang, Jue Wang, Tong Xia, Hui Liu, Ya You, Zhaohui Wang, Kun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
GABAA receptor
amphiregulin
macrophage
monocyte
pressure-overload hypertrophy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.670153/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.670153/full

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