Dynamic plasticity of prostate cancer intermediate cells during androgen receptor-targeted therapy

Dynamic plasticity of prostate cancer intermediate cells during androgen receptor-targeted therapy

Summary: Treatment-emergent small cell neuroendocrine prostate cancer (t-SCNC) is associated with an epithelial lineage switch from an androgen receptor (AR)-positive to neuroendocrine (NE)-marker-positive status. Understanding the potential for reversibility of this aggressive disease state has bee...

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Bibliographic Details
Main Authors: Harkirat S. Sandhu, Kensey L. Portman, Xianxiao Zhou, Julia Zhao, Alexander Rialdi, John P. Sfakianos, Ernesto Guccione, Natasha Kyprianou, Bin Zhang, David J. Mulholland
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722009299

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http://www.sciencedirect.com/science/article/pii/S2211124722009299

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