Heparanase Modulates Chromatin Accessibility

Heparanase is the sole endoglucuronidase that degrades heparan sulfate in the cell surface and extracellular matrix (ECM). Several studies have reported the localization of heparanase in the cell nucleus, but the functional role of the nuclear enzyme is still obscure. Subjecting mouse embryonic fibr...

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Bibliographic Details
Main Authors: Honglian Li, Hua Zhang, Amelie Wenz, Ziqi Kang, Helen Wang, Israel Vlodavsky, Xingqi Chen, Jinping Li
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/6/891