Stromal Cell-Derived Factor 1 Protects Brain Vascular Endothelial Cells from Radiation-Induced Brain Damage

Stromal Cell-Derived Factor 1 Protects Brain Vascular Endothelial Cells from Radiation-Induced Brain Damage

Stromal cell-derived factor 1 (SDF-1) and its main receptor, CXC chemokine receptor 4 (CXCR4), play a critical role in endothelial cell function regulation during cardiogenesis, angiogenesis, and reendothelialization after injury. The expression of CXCR4 and SDF-1 in brain endothelial cells decrease...

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Bibliographic Details
Main Authors: Jong-Ik Heo, Kwang Il Kim, Sang-Keun Woo, Joong Sun Kim, Kyu Jin Choi, Hae-June Lee, Kwang Seok Kim
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
sdf-1
cxcr4
ionizing radiation
endothelial dysfunction
senescence
brain disorder
Online Access:https://www.mdpi.com/2073-4409/8/10/1230

Internet

https://www.mdpi.com/2073-4409/8/10/1230

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