Endocytosis as a critical regulator of hematopoietic stem cell fate —implications for hematopoietic stem cell and gene therapy

Abstract Hematopoietic stem cells (HSCs) have emerged as one of the most therapeutically significant adult stem cells, paving way for a range of novel curative regimens over decades. HSCs are transplanted, either directly or post restorative genetic engineering in order to repopulate a healthy hemat...

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Bibliographic Details
Main Authors: Prathibha Babu Chandraprabha, Saravanabhavan Thangavel
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-024-03927-6