A conserved sequence in the small intracellular loop of tetraspanins forms an M-shaped inter-helix turn

Abstract Tetraspanins are a family of small proteins with four transmembrane segments (TMSs) playing multiple roles in human physiology. Nevertheless, we know little about the factors determining their structure. In the study at hand, we focus on the small intracellular loop (SIL) between TMS2 and T...

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Bibliographic Details
Main Authors: Nikolas Reppert, Thorsten Lang
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-07243-y