Arginase-1 promotes lens epithelial-to-mesenchymal transition in different models of anterior subcapsular cataract

Arginase-1 promotes lens epithelial-to-mesenchymal transition in different models of anterior subcapsular cataract

Abstract Background Arginase-1 (ARG1) promotes collagen synthesis and cell proliferation. ARG1 is highly expressed in various tumour cells. The mechanisms of ARG1 in epithelial-to-mesenchymal transition (EMT)-associated cataracts were studied herein. Methods C57BL/6 mice, a human lens epithelial cel...

Full description

Bibliographic Details
Main Authors: Qingyu Li, Yuchuan Wang, Luoluo Shi, Qing Wang, Guang Yang, Lin Deng, Ye Tian, Xia Hua, Xiaoyong Yuan
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cell Communication and Signaling
Subjects:
ARG1
Anterior subcapsular cataract
Posterior capsular opacification
Arginase-related pathway
CB-1158
Online Access:https://doi.org/10.1186/s12964-023-01210-4

Internet

https://doi.org/10.1186/s12964-023-01210-4

Similar Items