Fibronectin binding protein B binds to loricrin and promotes corneocyte adhesion by Staphylococcus aureus

The first step during skin colonization by is its adhesion to corneocytes. Da Costa et al. show that the cell wall-anchored fibronectin binding protein B (FnBPB) of S. aureus binds to loricrin. Applying single cell force spectroscopy, they demonstrate that this interaction promotes adhesion of S. au...

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Bibliographic Details
Main Authors: Thaina M. da Costa, Albertus Viljoen, Aisling M. Towell, Yves F. Dufrêne, Joan A. Geoghegan
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30271-1