Regulating Oral Biofilm from Cariogenic State to Non-Cariogenic State via Novel Combination of Bioactive Therapeutic Composite and Gene-Knockout

Regulating Oral Biofilm from Cariogenic State to Non-Cariogenic State via Novel Combination of Bioactive Therapeutic Composite and Gene-Knockout

The objectives were to investigate a novel combination of gene-knockout with antimicrobial dimethylaminohexadecyl methacrylate (DMAHDM) composite in regulating oral biofilm from a cariogenic state toward a non-cariogenic state. A tri-species biofilm model included cariogenic <i>Streptococcus m...

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Bibliographic Details
Main Authors: Hong Chen, Yingming Yang, Michael D. Weir, Quan Dai, Lei Lei, Negar Homayounfar, Thomas W. Oates, Kai Yang, Ke Zhang, Tao Hu, Hockin H. K. Xu
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Microorganisms
Subjects:
multi-species biofilm
<i>S. mutans</i><i>rnc</i> gene-knockout
bioactive composite
regulating biofilm composition
biofilm–material interactions
dental caries
Online Access:https://www.mdpi.com/2076-2607/8/9/1410

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https://www.mdpi.com/2076-2607/8/9/1410

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