Rare additional chromosomal abnormalities in acute promyelocytic leukaemia resulting in rapidly fatal disease: report of a case

Rare additional chromosomal abnormalities in acute promyelocytic leukaemia resulting in rapidly fatal disease: report of a case

Abstract Background Acute promyelocytic leukaemia results from reciprocal translocation between the long arms of chromosomes 15 and 17. This translocation leads to the formation of chimeric gene, which is both the diagnostic marker as well as the therapeutic target of the disease. Additional chromos...

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Bibliographic Details
Main Authors: Ahmed Maseh Haidary, Sarah Noor, Sahar Noor, Maryam Ahmad, Ahmad Walid Yousufzai, Ramin Saadaat, Zeeshan Ansar Ahmed, Abdul Jamil Rasooli, Ahmad Shekib Zahier, Haider Ali Malakzai, Abdul Sami Ibrahimkhil, Samuel Sharif, Mohammad Sarwar Anwari, Abdul Hadi Saqib, Tawab Baryali, Najla Nasir
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:eJHaem
Subjects:
acute promyelocytic leukaemia (APL)
additional chromosomal abnormalities (ACA)
fatal disease
rare
Online Access:https://doi.org/10.1002/jha2.349

Internet

https://doi.org/10.1002/jha2.349

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