Leishmania donovani Exploits Tunneling Nanotubes for Dissemination and Propagation of B Cell Activation

Leishmania donovani Exploits Tunneling Nanotubes for Dissemination and Propagation of B Cell Activation

ABSTRACT Polyclonal B cell activation and the resulting hypergammaglobulinemia are a detrimental consequence of visceral leishmaniasis (VL); however, the mechanisms underlying this excessive production of nonprotective antibodies are still poorly understood. Here, we show that a causative agent of V...

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Bibliographic Details
Main Authors: Tanja Stögerer, Sasha Silva-Barrios, Liseth Carmona-Pérez, Sharada Swaminathan, Linh Thuy Mai, Louis-Philippe Leroux, Maritza Jaramillo, Albert Descoteaux, Simona Stäger
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
B cells
tunneling nanotubes
polyclonal B cell activation
Leishmania donovani
Leishmania
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05096-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05096-22

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