The differential interaction of Brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens.

BACKGROUND:During evolution, innate immunity has been tuned to recognize pathogen-associated molecular patterns. However, some alpha-Proteobacteria are stealthy intracellular pathogens not readily detected by this system. Brucella members follow this strategy and are highly virulent, but other Bruce...

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Main Authors: Elías Barquero-Calvo, Raquel Conde-Alvarez, Carlos Chacón-Díaz, Lucía Quesada-Lobo, Anna Martirosyan, Caterina Guzmán-Verri, Maite Iriarte, Mateja Mancek-Keber, Roman Jerala, Jean Pierre Gorvel, Ignacio Moriyón, Edgardo Moreno, Esteban Chaves-Olarte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2691993?pdf=render