Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response
Abstract Microglia, resident immunocompetent cells of the central nervous system, can display a range of reaction states and thereby exhibit distinct biological functions across development, adulthood and under disease conditions. Distinct gene expression profiles are reported to define each of thes...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | Molecular Brain |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13041-021-00794-7 |