Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response

Abstract Microglia, resident immunocompetent cells of the central nervous system, can display a range of reaction states and thereby exhibit distinct biological functions across development, adulthood and under disease conditions. Distinct gene expression profiles are reported to define each of thes...

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Bibliographic Details
Main Authors: Lara Friess, Mathilde Cheray, Lily Keane, Kathleen Grabert, Bertrand Joseph
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-021-00794-7