Combination of ebselen and hydrocortisone substantially reduces nitrogen mustard-induced cutaneous injury

The purpose of the present study was to investigate the vesicant countermeasure effects of hydrocortisone (HC) and ebselen (EB-1), administered as monotherapy or as a combination treatment. The mouse ear vesicant model (MEVM) was utilized and test doses of HC (0.016, 0.023, 0.031, 0.047, 0.063, 0.12...

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Bibliographic Details
Main Authors: Hemanta C Rao Tumu, Benedette J. Cuffari, Blase Billack
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Toxicology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X21000360