Drug Repurposing to Inhibit Histamine <i>N</i>-Methyl Transferase

Drug Repurposing to Inhibit Histamine <i>N</i>-Methyl Transferase

Lower activity of the histaminergic system is associated with neurological disorders, including Alzheimer’s disease (AD). Thus, the enhancement of histaminergic neurotransmission by inhibition of histamine <i>N</i>-methyl transferase (HNMT), which degrades histamine, appears as an import...

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Bibliographic Details
Main Authors: Elvia Mera Jiménez, Teresa Żołek, Paola Gabriela Hernández Perez, Rene Miranda Ruvalcaba, María Inés Nicolás-Vázquez, Maricarmen Hernández-Rodríguez
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
drug repurposing
histamine <i>N</i>-methyl transferase
computational studies
molecular docking studies
molecular dynamics simulations
Online Access:https://www.mdpi.com/1420-3049/28/2/576

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https://www.mdpi.com/1420-3049/28/2/576

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