The Role of Hypoxia in Improving the Therapeutic Potential of Mesenchymal Stromal Cells. A Comparative Study From Healthy Lung and Congenital Pulmonary Airway Malformations in Infants

The Role of Hypoxia in Improving the Therapeutic Potential of Mesenchymal Stromal Cells. A Comparative Study From Healthy Lung and Congenital Pulmonary Airway Malformations in Infants

Mesenchymal stromal cells (MSCs) play an important role in the field of regenerative medicine thanks to their immunomodulatory properties and their ability to secrete paracrine factors. The use of MSCs has also been tested in children with congenital lung diseases inducing fibrosis and a decrease in...

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Bibliographic Details
Main Authors: Serena Silvestro, Francesca Diomede, Luigi Chiricosta, Valeria Domenica Zingale, Guya Diletta Marconi, Jacopo Pizzicannella, Andrea Valeri, Maria Antonietta Avanzini, Valeria Calcaterra, Gloria Pelizzo, Emanuela Mazzon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
hypoxia
mesenchymal stromal cells
lung
congenital pulmonary airway malformations
transcriptomic analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.868486/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.868486/full

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